Molecular Biology
Dihedral Angles and the Ramachandran Plot: Principles and Applications
The article gives an overview of dihedral angles (phi, psi, omega) and examines the Ramachandran plot's role in assessing protein structure validity through dihedral angles,…
A nucleic acid binding protein is a type of protein that interacts with DNA or RNA molecules through specific or nonspecific binding domains, playing crucial…
Epigenetic Modifications in Gene Regulation and Cancer
Introduction Epigenetic modifications, which involve changes to the genome without altering the DNA sequence, play a crucial role in regulating gene expression. These modifications include…
The Tryptophan (trp) operon in E-coli
Introduction to the trp Operon The trp operon of E. coli controls the synthesis of enzymes required for the biosynthesis of the amino acid tryptophan.…
Lactose Operon: Structure and regulation of lac operon
The lac operon is a negative control system consist of a promoter (P), an operator (O), and three structural genes, lacZ, lacY and lacA expressed…
Detailed Properties of Genetic code
The genetic code is composed of nucleotide triplets code in which each codon in an mRNA specifies one amino acid. Genetic code was cracked by…
The Wobble Hypothesis, proposed by Francis Crick in 1966, explains the degeneracy of the genetic code. The hypothesis attributes this degeneracy to imprecise pairing between the…
Chromosomal DNA isolation and Plasmid DNA isolation
DNA extraction employs cell disruption and separation techniques to isolate DNA from cellular material. Subsequent purification steps, often involving binding to a matrix, remove contaminants,…
